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Ontario Cancer Institute Toronto General Research Institute Toronto Rehabilitation Institute Toronto Western Research Institute
  • Located at the Princess Margaret Cancer Centre, Toronto, Ontario
  • Research foci: cancer— genomics, informatics, molecular biology, clinical trials, signalling pathways, structural biology and biophysics.
  • 361 scientists and clinician-scientists
  • $162M external funding
  • more
  • Located at the Toronto General Hospital, Toronto, Ontario
  • Research foci: cardiology, transplantation, immunology and infectious disease
  • 230 scientists and clinician-scientists
  • $73M external funding
  • more
  • Located at Toronto Rehab, Toronto, Ontario
  • Research foci: rehabilitation sciences, cardiopulmonary fitness and mobility
  • 119 scientists and clinician-scientists
  • $8M external funding
  • more
  • Located at the Toronto Western Hospital, Toronto, Ontario
  • Research foci: Neural and visual sciences, musculoskeletal disease and community and population health
  • 159 scientists and clinician-scientists
  • $35M external funding
  • more


The ORT Times August Issue Now Available
Aug 18, 2014

Welcome to The ORT Times!

The UHN Office of Research Trainees (ORT) is proud to announce the August 2014 ‘Summer Lite’ issue of The ORT Times! The ORT Times is a monthly e-newsletter for UHN trainees that features news and editorials about trainee life, articles to help developing researchers get the most out of their training experience at UHN, and tips on career development.

Read the full August 2014 issue online now.

Full Story

Parkinson's Disease: Negative Expectations Decrease Benefit of Therapy
Aug 13, 2014

A patient’s thoughts and expectations can impact the effectiveness of their therapy. The placebo effect is widely recognized in medical research. Here, a patient’s expectations can lead them to experience a benefit when they believe their treatment is effective. This phenomenon justifies the need for using a placebo or sugar pill (a pill that contains no active medication) comparator in clinical research trials evaluating new therapies. A little recognized and much less studied effect of patient expectation has been termed the lessebo effect. Here, clinical trial participants who know that they could receive either an active drug or a sugar pill experience a decreased benefit from the active drug.

A study published by TWRI Senior Scientist Dr. Anthony Lang demonstrated for the first time the presence and strength of the lessebo effect in clinical trials assessing the effectiveness of dopamine agonists, a class of drugs used to manage movement disturbances associated with Parkinson's disease (PD).

Full Story

August Issue of NRx Now Online
Aug 08, 2014

The August issue of NRx is now available. This monthly e-newsletter highlights the latest research from UHN’s five research institutes.

In this issue read about:
> A new anti-cancer therapy entering clinical trials
> The link between obesity and depression
> An HIV treatment linked to low birth weights
> Nanotechnology to visualize and treat cancer
> Barriers to breast reconstruction surgery
> The discovery of a new type of motion sickness
Other stories include UHN recipients of the Ontario Early Researcher Awards, UHN’s Inventors of the Year, and other awards and recognitions.

Read these stories and more in the August issue, online here. To read other issues, see the NRx Archive.

Full Story


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